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Cancer drug discovery relies mostly on testing the effects of therapeutics in tumor cell lines. However, drugs optimized to be highly effective on the 2D cultures are often lack of showing the expected efficacy on clinical trials. Substantial research efforts have demonstrated that 3D cell culture systems can better mimic and predict biological responses of living organisms. 3D in vitro tumor models are particularly useful to recapitulate tumor heterogeneity and microenvironment, fostering the discovery of therapeutics with improved clinical efficiency. Creative Bioarray believes that the evaluation of drug efficacy early during development can help to identify sources of potential drug resistance, and the read-outs of drug efficacy need to be capable of providing a specific quantitative measurement for our customers. Thus, we provide the adequacy of the assays for drug efficacy read-out measurements, and all these measurements are carefully evaluated and discussed.



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    Francis Djibo