I would definitely check that mod_perl is running.
See http://webwork.maa.org/wiki/Installation_Manual_for_2.13_on_Ubuntu_16.04#Apache_2_and_mod_perl
Further test Apache by connecting to "http://localhost/server-info" using a browser on your machine (or or from a browser on a remote machine in the math.yourschool.edu domain) and you will see a page listing various information about Apache. In particular under Server Settings you should see
Server Version: Apache/2.4.18 (Ubuntu) mod_apreq2-20090110/2.8.0 mod_perl/2.8.0 Perl/v5.22.1