What happens when you run "ls -l /etc/systemd/system/webwork2.service"? That should show a link to /opt/webwork/webwork2/conf/webwork2.service.
What about when you run "ls /etc/systemd/system/multi-user.target.wants"? That should also show a link to /opt/webwork/webwork2/conf/webwork2.service.
You should see both. If either of those are shown, but not both, then delete the one that is shown, and run "sudo systemctl enable /opt/webwork/webwork2/conf/webwork2.service". After running that command you should see both of the links above.
If that still does not fix the problem, then you might have a corrupt file system. At least that is one reason I can think of that this might happen.